Healthy Longevity Clinic

Cardiovascular prevention

Explore the questions behind healthy longevity. Understand the evidence, its possibilities and its limits.

3 articles

An empty table extends from a short, ring-shaped CT scanner in a softly lit room.

Coronary calcium score or CT angiography: which question does each answer?

A heart CT can help answer an important question about prevention or chest symptoms—but different scans reveal different things. A calcium score measures hardened plaque, while CT angiography shows the arteries and their narrowing in more detail. Understanding that difference helps you and your clinician choose the information that can actually guide your care.

Healthy Longevity Science5 min read

A terracotta paper liver silhouette sits behind a small sage DNA double-helix symbol.

Cardiovascular prevention

Cholesterol gene editing: what early human studies have shown

Imagine treating high cholesterol with a single infusion that helps the liver keep LDL levels lower for years. Gene editing is moving that possibility into human research. Early studies have produced substantial reductions in blood fats, opening a new chapter in prevention—while leaving the long-term benefits and risks to be established.

Healthy Longevity Science5 min read

A terracotta heart sculpture stands beside an unlabeled sample tube held upright in a small ivory holder.

Cardiovascular prevention

High Lp(a): what the HORIZON report means for prevention

Some cardiovascular risk is inherited, and lipoprotein(a), or Lp(a), can reveal a part that routine cholesterol tests miss. Knowing your level can help shape prevention even while new treatments are being tested. The first major HORIZON result was disappointing: lowering Lp(a) with pelacarsen did not establish the hoped-for reduction in serious events. Here is what that finding means for the science—and what a high result can still help you do today.

Healthy Longevity Science4 min read