Healthy Longevity Clinic

Blood and plasma therapies

Explore the questions behind healthy longevity. Understand the evidence, its possibilities and its limits.

4 articles

Four sealed blood-sample tubes in a rack, with a clear empty multiwell plate and a closed teal notebook.

Plasma exchange and aging clocks: what the human trial found

Could changing the proteins circulating in our blood influence aging? Plasma-exchange research is exploring that possibility. A small human study found encouraging changes in some biological-age measurements partway through treatment, raising new questions about how the procedure affects the body. To understand the finding, it helps to know what an aging clock measures, why the treatment combination matters, and what researchers still need to learn about lasting health benefits.

Healthy Longevity Science5 min read

A white rat beside three sealed tubes of pale fluid, separated by a transparent partition.

Blood and plasma therapies

Young plasma and E5: what the rat studies actually show

Blood carries much more than oxygen and nutrients. Its liquid component, plasma, contains signals that help tissues communicate—and some may influence how we age. E5 research explores whether selected components from young pigs’ plasma can support healthier aging. Small rat studies have reported encouraging changes in function, molecular age and lifespan. The challenge now is to understand what drives those effects and whether they can become a useful treatment for people.

Healthy Longevity Science5 min read

Blood and plasma therapies

Therapeutic plasma exchange: changes over time and biological-age research

Healthy Longevity Clinic’s longitudinal follow-up recorded LDL cholesterol falling from 165 to 64 mg/dL before the fifth therapeutic plasma exchange (TPE) session. A second report tracked metals, BPA, pesticide metabolites, mycotoxins and PFAS over three months. A controlled 2025 study adds biological-age findings, including a 2.61-year reduction with TPE plus IVIG at its intermediate assessment.

Healthy Longevity Science5 min read

A sealed pale plasma collection bag on an ivory tray beside an unbranded firefighter helmet and protective gloves.

Blood and plasma therapies

Can plasma donation remove PFAS and microplastics?

Repeated plasma donation lowered selected PFAS blood levels in a randomized trial of 285 Australian fire-service personnel. After a year, PFOS fell by an average of 2.9 ng/mL in the plasma group. That is a real measured effect. It does not establish permanent clearance from the whole body or better health, and the findings cannot be transferred to microplastics.

Healthy Longevity Science11 min read