Healthy Longevity ScienceExplore the questions behind healthy longevity. Understand the evidence, its possibilities and its limits.
4 articles
In one person followed at HLC, LDL cholesterol fell from 165 to 64 mg/dL between measurements before the first and fifth plasma-exchange sessions. This unpublished observation, without a control group, raises questions for further study. We compare it with a second descriptive exposure-marker report and a separate randomized biological-age trial.
Blood and plasma therapiesCould changing the proteins circulating in our blood influence aging? Plasma-exchange research is exploring that possibility. A small human study found encouraging changes in some biological-age measurements partway through treatment, raising new questions about how the procedure affects the body. To understand the finding, it helps to know what an aging clock measures, why the treatment combination matters, and what researchers still need to learn about lasting health benefits.
Blood and plasma therapiesBlood carries much more than oxygen and nutrients. Its liquid component, plasma, contains signals that help tissues communicate—and some may influence how we age. E5 research explores whether selected components from young pigs’ plasma can support healthier aging. Small rat studies have reported encouraging changes in function, molecular age and lifespan. The challenge now is to understand what drives those effects and whether they can become a useful treatment for people.
Blood and plasma therapiesRepeated plasma donation lowered selected PFAS blood levels in a randomized trial of 285 Australian fire-service personnel. After a year, PFOS fell by an average of 2.9 ng/mL in the plasma group. That is a real measured effect. It does not establish permanent clearance from the whole body or better health, and the findings cannot be transferred to microplastics.